Everything you want to know before you start.

Marnie Predovich is the co-founder and lead clinical provider at Colorado Hormones. ACNPC-AG stands for Adult-Gerontology Acute Care Nurse Practitioner, a certification from the American Association of Critical-Care Nurses. She also holds advanced BHRT training through WorldLink Medical Academy and is licensed to practice telehealth in Colorado.

No. We do hormone optimization and related wellness care. We don't manage chronic conditions unrelated to hormones, prescribe medications for acute illnesses, or handle emergency care. If you need a primary care provider, you'll want one in addition to working with us.

Mostly. Your first visit can be in person at your home or office, and follow-up visits are by video. Bloodwork is drawn at your home or office, and medications are shipped to your door.

No. We're cash-pay only. Insurance billing requires prior authorizations and coverage approvals that often override clinical judgment. Cash-pay removes those barriers and lets us recommend what's actually right for your case. You know the cost before you start.

Not at this time. We're not currently able to see Medicare patients. If you'd like to be notified if that changes, leave your name and email below and we'll reach out.

We'll only use this to contact you about Medicare availability.

We see adult men and women who are Colorado residents. Telehealth regulations require patients to be physically in Colorado at the time of their visits. We're not able to see minors or residents of other states.

A few things. We test comprehensively before we treat anything. We use bioidentical hormones, not synthetic. You have one provider throughout your entire program, not a rotating staff. And we build your protocol around your labs and your symptoms together, not a standard template.

Book a free 15-minute welcome call. We'll talk through how you're feeling, explain how the program works, and decide together if we're the right fit. If you move forward, we enroll you and schedule your labs.

It's a conversation, not a medical appointment. We won't give diagnoses or prescriptions on the call. We'll talk about where you are, what you've tried, and what you're hoping to change. Then we'll explain what the program looks like and answer any questions you have.

Labs and symptoms together. No one is pre-approved before we see your numbers and hear how you're feeling. Your initial labs and provider review give us the information we need to determine whether hormone optimization is appropriate for you. If it isn't, we refund your program fee in full, you keep your results, and we tell you clearly what we found.

No. Bloodwork and your first visit come to you, at your home or office, and follow-up visits are by video. Medications ship to your door. You don't need to travel to a lab or clinic.

After your welcome call, you'll schedule your initial consultation and labs. Once your results are back, you and your provider build your protocol together. The full process from welcome call to protocol typically takes a few weeks, depending on lab turnaround.

"Normal" lab ranges are statistical averages designed to detect disease. A result in range simply means you're not an outlier in the population. Optimal is where you actually feel and perform your best, which often sits higher in the range. We evaluate your numbers alongside your symptoms, not in isolation.

A few reasons. Normal ranges are wide. A result at the bottom and one at the top are both technically normal but can feel very different. We also look at hormones most standard panels skip, and we consider ratios between hormones. And cells can lose sensitivity to hormones even when circulating levels look adequate. Your symptoms matter. We factor in both.

We coordinate mobile draw services that come to your home or office. You schedule the appointment, they come to you. No driving to a lab, no waiting rooms. Results go directly to your provider for review.

Your initial labs are drawn at home or your office and are included in the 4-Month Reset. During the Reset, we draw more frequently while we're adjusting your protocol. From month 5 onward, monitoring moves to a quarterly cadence, and labs and phlebotomy are included in your ongoing care. Your provider will tell you exactly when you're due for bloodwork.

First, a free welcome call. If it's a fit, you enroll in the 4-Month Reset (months 1-4): a phlebotomist draws your bloodwork at home or your office, and your provider reviews it with you. From there we build your protocol, with monthly check-ins while we adjust. From month 5 onward, you move into Ongoing Care: visits shift to quarterly, labs and phlebotomy are included, and we fine-tune your protocol as your body adapts, for as long as you continue.

The 4-Month Reset is a four-month program paid upfront. After that, Ongoing Care is month-to-month with no contracts, for as long as you want to continue. We ask for a four-month commitment upfront because that's how long it takes to build and dial in a protocol. Hormone optimization is not a quick fix.

We offer topical creams and injections. Your provider recommends the delivery method that fits your protocol and your preferences. You're not locked into one option. Medications are compounded and shipped to your door.

We tell you clearly, refund your program fee in full, and you keep your lab results. If your numbers don't support hormone optimization, or if hormones aren't the right tool for what you're experiencing, we'll explain what we found and what we'd suggest instead. We'd rather be straight with you than take your money and disappoint you.

We run a comprehensive panel: estrogen (E1, E2, E3), progesterone, testosterone, SHBG, DHEA, cortisol, and a full thyroid panel including TSH, Free T3, Free T4, and thyroid antibodies. We also check fasting insulin, glucose, and inflammatory markers. Ratios between hormones matter as much as individual levels.

Bioidentical hormones are molecularly identical to the hormones your body produces. Synthetic hormones, like conjugated equine estrogens and synthetic progestins (Provera, Prempro), have a chemically altered structure. This matters clinically: synthetic progestins have been shown in research to increase breast cancer risk. Bioidentical progesterone has not, and some studies suggest it's protective. We use bioidentical hormones exclusively, derived from plant sources and compounded to your specific labs and symptoms.

Yes. Perimenopause, menopause, and post-menopause are all within our scope. Hormonal shifts during these stages affect energy, sleep, mood, weight, cognition, and more. We evaluate your labs and symptoms together, build a protocol around both, and adjust as your body changes.

This is exactly who we work with. Normal lab ranges are built to detect disease, not to measure where you feel your best. A number can be in range and still leave you well below optimal. On top of that, cells can resist hormones even when circulating levels look adequate. Your symptoms are clinically meaningful data. We use both.

The fear comes from the 2002 Women's Health Initiative, which studied women averaging 63 years old given Prempro, a conjugated equine estrogen paired with a synthetic progestin. That combination was associated with increased breast cancer risk. Bioidentical estradiol is not Prempro, and natural progesterone is not a synthetic progestin. The molecular structures differ, and the evidence base differs.

The DOPS randomized trial followed perimenopausal women on oral estradiol for more than 10 years and found reduced rates of cardiovascular events and no increased breast cancer rate. The WEST trial studied oral estradiol in post-menopausal women and found no increased breast cancer incidence compared to placebo. We're happy to walk through the relevant studies on your welcome call.

Estradiol plays a meaningful role in bone density. When estradiol declines at menopause and stays low, bone loss accelerates. The research on estradiol and fracture risk is substantial, and it's one of the reasons starting hormone therapy close to menopause, rather than years later, matters. We evaluate bone health markers as part of your overall picture.

A standard TSH test alone misses most thyroid dysfunction. We run Free T3, Free T4, and thyroid antibodies in addition to TSH. It's not uncommon for someone to have a normal TSH and still have thyroid dysfunction that shows up in the other markers.

The symptoms are often gradual: fatigue that doesn't improve with sleep, loss of muscle despite working out, low libido, brain fog, mood changes, weight gain around the midsection. Because the decline is slow, about 1% per year after 30, most men attribute it to stress or aging. Your symptom picture is the starting point. Labs tell us what we're working with.

Total testosterone, free testosterone, SHBG, LH, estradiol, DHT, DHEA, cortisol, a full thyroid panel (TSH, Free T3, Free T4), and metabolic markers including fasting insulin, CBC, and a comprehensive metabolic panel. Free testosterone is what your body actually uses, and it's what most standard panels skip.

A few reasons. Normal ranges are wide. A man at the bottom and one at the top are both "normal" but can feel completely different. Most panels also stop at total testosterone and skip free testosterone, which is what your cells actually use. And cells can lose sensitivity to hormones even when circulating levels look adequate. Your symptoms are clinically meaningful data. We use both.

When properly monitored, yes. Testosterone replacement therapy is a tool, not a default. We recommend it when it's clinically indicated and monitor your response at every phase.

The TRAVERSE trial, published in the New England Journal of Medicine in 2023, followed over 5,000 men with hypogonadism and pre-existing or elevated cardiovascular risk. It found no increased rate of major adverse cardiac events with testosterone therapy. We track estrogen, hematocrit, and PSA throughout your program.

The evidence doesn't support that. A comprehensive review published in the New England Journal of Medicine found no credible evidence that testosterone therapy increases prostate cancer risk, a conclusion consistent with 18 or more epidemiologic studies. We monitor PSA throughout your program and factor your full history into any recommendation.

Exogenous testosterone can suppress sperm production. If fertility is a concern, that's an important part of the conversation before starting any testosterone protocol. Bring it up on your welcome call or initial visit and we'll factor it into your plan.

The 4-Month Reset (months 1-4) is $2,400 paid in full and includes your initial labs and provider review. Ongoing Care (months 5+) is $199/month, no contracts, with labs and phlebotomy included. Medication costs are separate from program fees. No surprise bills. See our refund and cancellation terms.

Labs are included: your initial labs are part of the 4-Month Reset, and labs plus phlebotomy are included in Ongoing Care. Medication costs are separate. We're transparent about this upfront so you know the full picture before you start. Your provider will give you a clear estimate of medication costs during your initial consultation.

Yes. We offer Cherry financing for the 4-Month Reset. Rates vary based on credit and term. Cherry is a third-party financing service; approval is subject to their underwriting criteria.

In many cases, yes. HSA and FSA funds can often be used for cash-pay medical services and lab costs. We recommend checking with your plan administrator for your specific situation, since eligibility varies by account type and the specific services involved.